We've recently introduced a rate limit on outgoing e-mail sent via mail.ru.ac.za. Users of our webmail client can send e-mail to no more than a hundred recipients every hour, and people who use other e-mail clients can send e-mail to no more than a hundred recipients every half an hour. (Each e-mail address in the To:, Cc: or Bcc: field of an e-mail counts as a recipient, so the webmail limit means a hundred messages each with one recipient or ten messages each each with ten recipients, etc).
We've been monitoring the volumes of e-mail sent over the last few days and a few people will very occasionally hit the rate limits. For the most part, this change will not affect people -- the limit of 100 recipients every 30 minutes is fairly generous, and you're unlikely to hit it with normal use.
If you do hit the rate limit when sending e-mail, the mail servers will temporarily refuse to accept mail from you. Depending on what e-mail client you do, you'll either see this as an error message or your client will simply re-queue the message and try again later. Either way, the solution is to wait at least half an hour and then re-send the message. Note that this may require that you close your e-mail client, wait half an hour, and then re-open it (this depends on how your client is configured to retry sending messages).